Genetic polymorphisms of the CYP3A4, CTP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus
- Author
- HESSELINK, Dennis A; VAN SCHAIK, Ron H. N; VAN DER HEIDEN, Ilse P; VAN DER WERF, Marloes; SMAK GREGOOR, Peter J. H; LINDEMANS, Jan; WEIMAR, Willem; VAN GELDER, Teun
Department of Internal Medicine, Renal Transplant Unit, Department of Clinical Chemistry, and Hospital Pharmacy, Clinical Pharmacology Unit, Erasmus Medical Center, Netherlands - Source
Clinical pharmacology and therapeutics. 2003, Vol 74, Num 3, pp 245-254, 10 p ; ref : 46 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Calcineurine Ciclosporine Cytochrome P450 Glycoprotéine P Gène MDR1 Génotype Génétique Homme Inhibiteur Isozyme Métabolisme Pharmacocinétique Pharmacogénétique Polymorphisme Tacrolimus Voie orale Cytochrome CYP3A4 Cytochrome CYP3A5 Immunodépresseur Lactone Macrolide
- Keyword (en)
- Calcineurin Ciclosporin Cytochrome P450 P Glycoprotein MDR-1 gene Genotype Genetics Human Inhibitor Isozyme Metabolism Pharmacokinetics Pharmacogenetics Polymorphism Tacrolimus Oral administration Immunosuppressive agent Lactone Macrolide
- Keyword (es)
- Calcineurina Ciclosporina Citocromo P450 Glicoproteína P Gen MDR-1 Genotipo Genética Hombre Inhibidor Isozima Metabolismo Farmacocinética Farmacogenética Polimorfismo Tacrolimús Vía oral Inmunodepresor Lactona Macrólido
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02Q Immunomodulators
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15139168
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0009-9236(03)00168-1 
https://dx.doi.org/10.1016/S0009-9236(03)00168-1
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