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Methionine restriction selectively targets thymidylate synthase in prostate cancer cells

Author
SHAN LU1 ; CHEN, George L1 ; CHENGXI REN1 ; KWABI-ADDO, Bernard2 ; EPNER, Daniel E1
[1] Department of Medicine, VA Medical Center, Baylor College of Medicine, Medical Service (111H), 2002 Holcombe Blvd., Houston, TX 77030, United States
[2] Department of Pathology, VA Medical Center, Baylor College of Medicine, Houston, TX 77030, United States
Source

Biochemical pharmacology. 2003, Vol 66, Num 5, pp 791-800, 10 p ; ref : 49 ref

CODEN
BCPCA6
ISSN
0006-2952
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
Publisher
Elsevier Science, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
Folate Methionine Prostate neoplasms Thymidylate synthase
Keyword (fr)
Antidote Antiseptique Cholérétique Cible Méthionine Pharmacologie Thymidylate synthase Cancer de la prostate Tumeur de la prostate Aminoacide soufré Appareil génital mâle pathologie Appareil urinaire pathologie Enzyme Methyltransferases Prostate pathologie Transferases Tumeur maligne
Keyword (en)
Antidote Antiseptic Choleretic Target Methionine Pharmacology Thymidylate synthase Prostate cancer Prostate tumor Sulfur containing aminoacid Male genital diseases Urinary system disease Enzyme Methyltransferases Prostate disease Transferases Malignant tumor
Keyword (es)
Antídoto Antiséptico Colerético Blanco Metionina Farmacología Thymidylate synthase Cáncer de la próstata Tumor de la próstata Aminoácido azufrado Aparato genital macho patología Aparato urinario patología Enzima Methyltransferases Prostata patología Transferases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
15144106

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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