Structures and cytotoxic properties of trichoverroids and their macrolide analogues produced by saltwater culture of Myrothecium verrucaria
- Author
- AMAGATA, Taro1 ; RATH, Christopher1 ; RIGOT, Jérome F1 ; TARLOV, Nick1 ; TENNEY, Karen1 ; VALERIOTE, Frederick A2 ; CREWS, Phillip1
[1] Department of Chemistry and Biochemistry and Institute for Marine Sciences, University of California-Santa Cruz, Santa Cruz, California 95064, United States
[2] Josephine Ford Cancer Center, Detroit, Michigan 48202, United States - Source
Journal of medicinal chemistry (Print). 2003, Vol 46, Num 20, pp 4342-4350, 9 p ; ref : 42 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Acylate Acétal Analyse structurale Animal Anticancéreux Cellule tumorale Composé pentacyclique Composé polycyclique Cytotoxicité Diterpène Homme Hétérocycle oxygène In vitro Isolement Lactone Lignée cellulaire Macrolide Milieu marin Myrothecium Origine microbienne Souris Terpénoïde Trichothécène Mophytocène C Myrothecium uerrucaria Roridine E(3-hydroxy) Trichoverrine B(13-acetyl) Fungi Imperfecti Fungi Mammalia Rodentia Thallophyta Vertebrata
- Keyword (en)
- Biological activity Acylate Acetal Structural analysis Animal Antineoplastic agent Tumor cell Pentacyclic compound Polycyclic compound Cytotoxicity Diterpene Human Oxygen heterocycle In vitro Isolation Lactone Cell line Macrolide Marine environment Myrothecium Microbial origin Mouse Terpenoid Trichothecene Fungi Imperfecti Fungi Mammalia Rodentia Thallophyta Vertebrata
- Keyword (es)
- Actividad biológica Acilato Acetal Análisis estructural Animal Anticanceroso Célula tumoral Compuesto pentacíclico Compuesto policíclico Citotoxicidad Diterpeno Hombre Heterociclo oxígeno In vitro Aislamiento Lactona Línea celular Macrólido Medio marino Myrothecium Origen microbiano Ratón Terpenoide Tricoteceno Fungi Imperfecti Fungi Mammalia Rodentia Thallophyta Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05F Applied microbiology / 002A05F03 Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents / 002A05F03C Chemotherapic agents
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15168619
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm030090t 
https://dx.doi.org/10.1021/jm030090t
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