Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo
- Author
- BUTLER, Lisa M1 ; AGUS, David B2 ; SCHER, Howard I3 ; HIGGINS, Brian2 ; ROSE, Adam1 ; CORDON-CARDO, Carlos4 ; THALER, Howard T4 ; RIFKIND, Richard A1 ; MARKS, Paul A1 ; RICHON, Victoria M1
[1] Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, United States
[2] Laboratory of Tumor Biology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, United States
[3] Genitourinary Oncology Service, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, United States
[4] Department of Epidemiology and Biostatistics Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, United States - Source
Cancer research (Baltimore). 2000, Vol 60, Num 18, pp 5165-5170 ; ref : 32 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Acétylation Analogue Animal Anticancéreux Antigène spécifique prostate Apoptose Cellule tumorale Histone Homme Hydroxamique acide polymère In vitro In vivo Inhibiteur enzyme Lignée cellulaire établie Mort cellulaire Multiplication cellulaire Prostate Relation dose réponse Souris Traitement Tumeur maligne Histone deacetylase SAHA Appareil génital mâle pathologie Appareil urinaire pathologie Mammalia Prostate pathologie Rodentia Vertebrata
- Keyword (en)
- Biological activity Acetylation Analog Animal Antineoplastic agent Prostate specific antigen Apoptosis Tumor cell Histone Human Hydroxamic acid polymer In vitro In vivo Enzyme inhibitor Established cell line Cell death Cell proliferation Prostate Dose activity relation Mouse Treatment Malignant tumor Male genital diseases Urinary system disease Mammalia Prostate disease Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Acetilación Análogo Animal Anticanceroso Antigeno específico prostata Apoptosis Célula tumoral Histona Hombre Hidroxámico ácido polímero In vitro In vivo Inhibidor enzima Línea celular establecida Muerte celular Multiplicación celular Prostata Relación dosis respuesta Ratón Tratamiento Tumor maligno Aparato genital macho patología Aparato urinario patología Mammalia Prostata patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1518035
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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