Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
- Author
- LUCIANO, Frederic1 ; JACQUEL, Arnaud1 ; COLOSETTI, Pascal1 ; HERRANT, Magali1 ; CAGNOL, Sebastien2 ; PAGES, Gilles2 ; AUBERGER, Patrick1
[1] INSERM Unit 526, LNC Label, Faculté de Médecine, 28 Avenue de Valombrose, 06107 Nice, France
[2] UMR CNRS 6547, Centre Antoine Lacassagne, Avenue de valombrose, 06100 Nice, France - Source
Oncogene (Basingstoke). 2003, Vol 22, Num 43, pp 6785-6793, 9 p ; ref : 26 ref
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Bim Erkl/2 apoptosis proteasome
- Keyword (fr)
- Apoptose Dégradation Extracellular signal-regulated protein kinase Multicatalytic endopeptidase complex Phosphorylation Sérine Protéine Bim Enzyme Hydrolases Peptidases
- Keyword (en)
- Apoptosis Degradation Extracellular signal-regulated protein kinase Multicatalytic endopeptidase complex Phosphorylation Serine Enzyme Hydrolases Peptidases
- Keyword (es)
- Apoptosis Degradación Extracellular signal-regulated protein kinase Multicatalytic endopeptidase complex Fosforilación Serina Enzima Hydrolases Peptidases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15231110
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1206792 
https://dx.doi.org/10.1038/sj.onc.1206792
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