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Detoxification of 4-hydroxynonenal (HNE) in keratinocytes: Characterization of conjugated metabolites by liquid chromatography/electrospray ionization tandem mass spectrometry

Author
ALDINI, Giancarlo1 ; GRANATA, Paola1 ; ORIOLI, Marica1 ; SANTANIELLO, Enzo2 ; CARINI, Marina1
[1] Istituto Chimico Farmaceutico Tossicologico, University of Milan, Viale Abruzzi 42, 20131 Milan, Italy
[2] Dipartimento di Scienze Precliniche LITA Vialba, University of Milan, Via G. B. Grassi 74, 20157 Milan, Italy
Source

Journal of mass spectrometry. 2003, Vol 38, Num 11, pp 1160-1168, 9 p ; ref : 20 ref

ISSN
1076-5174
Scientific domain
Biochemistry, molecular biology, biophysics; Analytical chemistry; Organic chemistry
Publisher
Wiley, Chichester
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
4-hydroxynonenal characterization glutathione-conjugated adducts keratinocytes liquid chromatography/electrospray ionization tandem mass spectrometry
Keyword (fr)
Analyse chimique Analyse quantitative Chromatographie phase liquide Cinétique Composé conjugué Détoxication Electrospray Enaldéhyde Glutathion Kératinocyte Métabolite Méthode couplée Nonénal(4-hydroxy) Peau Spectrométrie masse tandem Stress oxydatif Nonénal(4-hydroxy)
Keyword (en)
Chemical analysis Quantitative analysis Liquid chromatography Kinetics Conjugated compound Detoxification Electrospray Enaldehyde Glutathione Keratinocyte Metabolite Coupled method Skin Mass spectrometry MS/MS Oxidative stress
Keyword (es)
Análisis químico Análisis cuantitativo Cromatografía fase líquida Cinética Compuesto conjugado Detoxicación Electrospray Enaldehido Glutatión Queratinocito Metabolito Método acoplado Piel Espectrometría masa en tándem Estrés oxidativo
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H01 Cell metabolism, cell oxidation

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A19 Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03A General aspects. Methods

Discipline
Molecular and cell biology Toxicology Vertebrates : skin, associated glands, phaneres, light organs, various exocrine glands, adipose tissue, connective tissue
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
15313528

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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