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The first enzymatic method for C-18F bond formation: the synthesis of 5'-[18F]-fluoro-5'-deoxyadenosine for imaging with PET

Author
MARTARELLO, Laurent1 ; SCHAFFRATH, Christoph2 ; HAI DENG2 ; GEE, Antony D1 ; LOCKHART, Andrew1 ; O'HAGAN, David2
[1] GlaxoSmithKline Pharmaceuticals, Translational Medicine and Technology, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2GG, United Kingdom
[2] School of Chemistry, University of St Andrews, Centre for Biomolecular Sciences, North Haugh, St Andrews, Fife KY16 9ST, United Kingdom
Source

Journal of labelled compounds & radiopharmaceuticals. 2003, Vol 46, Num 13, pp 1181-1189, 9 p ; ref : 9 ref

ISSN
0362-4803
Scientific domain
Biochemistry, molecular biology, biophysics; Organic chemistry; Pharmacology drugs
Publisher
Wiley, Chichester / Wiley, New York, NY
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Adénosylméthionine Aminoacide soufré Désoxyribonucléoside Fluor 18 Hydrogène Fluorure Marquage radioisotopique Purine nucléoside Réaction enzymatique Streptomyces Adénosine(5p-désoxy-5p-fluoro) Streptomyces cattleya Actinomycetales Actinomycetes Bactérie Streptomycetaceae
Keyword (en)
Adenosylmethionine Sulfur containing aminoacid Deoxyribonucleoside Fluorine 18 Hydrogen Fluorides Radiolabelling Purine nucleoside Enzymatic reaction Streptomyces Actinomycetales Actinomycetes Bacteria Streptomycetaceae
Keyword (es)
Adenosilmetionina Aminoácido azufrado Desoxirribonucleósido Hidrógeno Fluoruro Marcación radioisotópica Purina nucleósido Reacción enzimática Streptomyces Actinomycetales Actinomycetes Bacteria Streptomycetaceae
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31C Methods. Procedures. Technologies / 002A31C06 Bioconversions. Hemisynthesis

Discipline
Biotechnology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
15314611

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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