Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes
- Author
- LALOVIC, Bojan1 2 ; PHILLIPS, Brian2 ; RISLER, Linda L2 ; HOWALD, William3 ; SHEN, Danny D1 2 4
[1] Department of Pharmaceutics, University of Washington, Seattle, Washington, United States
[2] Departments of PharmaceuticClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
[3] Department of Medicinal Chemistry, University of Washington, Seattle, Washington, United States
[4] Department of Pharmacy, University of Washington, Seattle, Washington, United States - Source
Drug metabolism and disposition. 2004, Vol 32, Num 4, pp 447-454, 8 p ; ref : 39 ref
- CODEN
- DMDSAI
- ISSN
- 0090-9556
- Scientific domain
- Pharmacology drugs
- Publisher
- American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Analgésique narcotique Analyse quantitative Cytochrome P450 Foie Homme In vitro Intestin Isozyme Microsome Métabolisme Oxycodone Oxydation Appareil digestif Opiacés Pharmacocinétique
- Keyword (en)
- Narcotic analgesic Quantitative analysis Cytochrome P450 Liver Human In vitro Gut Isozyme Microsome Metabolism Oxycodone Oxidation Digestive system Opiates Pharmacokinetics
- Keyword (es)
- Analgésico narcotico Análisis cuantitativo Citocromo P450 Hígado Hombre In vitro Intestino Isozima Microsoma Metabolismo Oxicodona Oxidación Aparato digestivo Opiados Farmacocinética
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B05 Analgesics
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15604135
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1124/dmd.32.4.447 
https://dx.doi.org/10.1124/dmd.32.4.447
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