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Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae

Author
GORSKI, Marcin M1 ; ROMEIJN, Ron J1 ; EEKEN, Jan C. J1 ; DE JONG, Anja W. M1 2 ; VAN VEEN, Bert L1 2 ; SZUHAI, Karoly2 ; MULLENDERS, Leon H1 ; FERRO, Wouter1 ; PASTINK, Albert1
[1] Department of Toxicogenetics, Leiden University Medical Center (LUMC), Wassenaarseweg 72, 2333 AL Leiden, Netherlands
[2] Department of Molecular Cell Biology, LUMC, 2333 AL Leiden, Netherlands
Source

DNA repair. 2004, Vol 3, Num 6, pp 603-615, 13 p ; ref : 59 ref

ISSN
1568-7864
Scientific domain
Biochemistry, molecular biology, biophysics; Genetics
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Drosophila Histone H2Ax Homologous recombination Rad50
Keyword (fr)
Apoptose Cassure bicaténaire DNA bicaténaire Drosophila Histone Induction Recombinaison homologue Réparation Arthropoda Diptera Drosophilidae Insecta Invertebrata
Keyword (en)
Apoptosis Double strand break Double stranded DNA Drosophila Histone Induction Homologous recombination Repair Arthropoda Diptera Drosophilidae Insecta Invertebrata
Keyword (es)
Apoptosis Ruptura bicatenaria DNA bicatenario Drosophila Histona Inducción Recombinación homólogo Reparación Arthropoda Diptera Drosophilidae Insecta Invertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C07 Mutagenesis. Repair

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05B Bacteriology / 002A05B05 Growth, nutrition, cell differenciation

Discipline
Microbiology Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
15727644

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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