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Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid

Author
SANTOS, Webster L1 ; HEASLEY, Brian H2 ; JAROSZ, Renata3 ; CARTER, Karen M2 ; LYNCH, Kevin R3 ; MACDONALD, Timothy L2
[1] Department of Chemistry and Chemical Biology, 12 Oxford Street, Cambride, MA 02138, United States
[2] Department of Chemistry, University of Virginia, PO Box 400319, McCormick Road, Charlottesville, VA 22904, United States
[3] Department of Pharmacology, University of Virginia, PO Box 400319, McCormick Road, Charlottesville, VA 22904, United States
Source

Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 13, pp 3473-3476, 4 p

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Acide gras monoinsaturé Affinité Agoniste Amide gras Composé biomimétique Lysophosphatidique acide Phosphonate organique Relation structure activité Récepteur lysophospholipide edg1 Récepteur lysophospholipide edg2 Synthèse chimique Thiophosphorique acide Oléamide dérivé
Keyword (en)
Monounsaturated fatty acid Affinity Agonist Fatty amide Biomimetic compound Lysophosphatidic acid Organic phosphonate Structure activity relation edg1 lysophospholipid receptor edg2 lysophospholipid receptor Chemical synthesis Thiophosphoric acid
Keyword (es)
Acido graso monoinsaturado Afinidad Agonista Amida grasa Compuesto biomimético Lisofosfatídico ácido Fosfonato orgánico Relación estructura actividad Receptor lisofosfolípido edg1 Receptor lisofosfolípido edg2 Síntesis química Tiofosfórico ácido
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
15797309

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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