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Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs

Author
SUH, Young-Ger1 2 ; LEE, Kwang-Ok1 ; SEUNG JIN LEE1 ; SANG GEON KIM1 ; MOON, Sung-Hyun1 ; SEO, Seung-Yong1 ; LEE, Yong-Sil1 ; KIM, Seok-Ho1 ; PAEK, Seung-Mann1 ; KIM, Young-Ho3 ; LEE, Yun-Sang1 ; JAE MIN JEONG4
[1] College of Pharmacy, Pharmaceutical Chemistry, Seoul National University, San 56-1 Shinrim-Dong, Kwanak-Gu, Seoul 151-742, Korea, Republic of
[2] Center for Bioactive Molecular Hybrids, Yonsei University, Seoul 120-749, Korea, Republic of
[3] College of Pharmacy, Chungnam University, Taejon 305-764, Korea, Republic of
[4] College of Medicine, Seoul National University, Seoul 110-744, Korea, Republic of
Source

Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 13, pp 3487-3490, 4 p

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Acide carboxylique Alcool primaire Antiinflammatoire Carboxamide Composé tricyclique Composé vinylique Cyclooxygenase 2 Diterpène Hydrazide organique Imide In vitro Inhibiteur enzyme Mécanisme action Relation structure activité Synthèse chimique Terpénoïde Acanthoïque acide dérivé Pimarane dérivé Enzyme Oxidoreductases
Keyword (en)
Carboxylic acid Primary alcohol Antiinflammatory agent Carboxamide Tricyclic compound Vinylic compound Cyclooxygenase 2 Diterpene Organic hydrazide Imide In vitro Enzyme inhibitor Mechanism of action Structure activity relation Chemical synthesis Terpenoid Enzyme Oxidoreductases
Keyword (es)
Acido carboxílico Alcohol primario Antiinflamatorio Carboxamida Compuesto tricíclico Compuesto vinílico Cyclooxygenase 2 Diterpeno Hidrácida orgánica Imida In vitro Inhibidor enzima Mecanismo acción Relación estructura actividad Síntesis química Terpenoide Enzima Oxidoreductases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
15797312

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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