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Restoration of the glucocorticoid receptor function by the phosphodiester compound of vitamins C and E, EPC-K1 (L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,1 2-trimethyltridecyl)-2H-1-benzopyran-6-yl hydrogen phosphate] potassium salt), via a redox-dependent mechanism

Author
OKAMOTO, K1 ; TANAKA, H1 ; MAKINO, Y1 ; MAKINO, I1
[1] Second Department of Internai Medicine, Asahikawa Medicai College, Nishikagura, Asahikawa 078, Japan
Source

Biochemical pharmacology. 1998, Vol 56, Num 1, pp 79-86 ; ref : 44 ref

CODEN
BCPCA6
ISSN
0006-2952
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
Publisher
Elsevier Science, New York, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Acide ascorbique Activité biologique Animal Antioxydant Expression génique Glucocorticoïde Hamster Inflammation Ligand Lignée CHO Lignée cellulaire établie Mécanisme action Produit gène Récepteur biologique Récepteur nucléaire Site fixation Stress oxydatif Système redox Transduction signal Vitamine E EPCK 1 Hormone stéroïde Hormone surrénalienne Mammalia Rodentia Vertebrata
Keyword (en)
Ascorbic acid Biological activity Animal Antioxidant Gene expression Glucocorticoid Hamster Inflammation Ligand CHO cell line Established cell line Mechanism of action Gene product Biological receptor Nuclear receptor Binding site Oxidative stress Redox system Signal transduction E-Vitamins Steroid hormone Adrenal hormone Mammalia Rodentia Vertebrata
Keyword (es)
Acido ascórbico Actividad biológica Animal Antioxidante Expresión genética Glucocorticoide Hamster Inflamación Ligando Célula CHO Línea celular establecida Mecanismo acción Producto gene Receptor biológico Receptor nuclear Sitio fijación Stress oxidativo Sistema redox Transducción señal Vitamina E Hormona esteroide Hormona suprarrenal Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02N General and cellular metabolism. Vitamins

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1581688

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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