EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
- Author
- PAEZ, J. Guillermo1 2 ; JÄNNE, Pasi A1 2 ; NAOKI, Katsuhiko1 ; SASAKI, Hidefumi7 ; FUJI, Yoshitaka7 ; ECK, Michael J1 3 ; SELLERS, William R1 2 4 ; JOHNSON, Bruce E1 2 ; MEYERSON, Matthew1 2 3 4 ; LEE, Jeffrey C1 3 ; TRACY, Sean1 ; GREULICH, Heidi1 2 ; GABRIEL, Stacey4 ; HERMAN, Paula1 ; KAYE, Frederic J5 ; LINDEMAN, Neal6 ; BOGGON, Titus J1 3
[1] Departments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, United States
[2] Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States
[3] Departments of Pathology and Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, United States
[4] The Broad Institute at MIT and Harvard, Cambridge, MA 02142, United States
[5] Genetics Branch, National Cancer Institute, National Naval Medical Center, Bethesda, MD 20889, United States
[6] Department of Pathology, Brigham and Women's Hospital, Boston MA 02115, United States
[7] Department of Surgery 2, Nagoya City University Medical School, Nagoya 467-8601, Japan - Source
Science (Washington, D.C.). 2004, Vol 304, Num 5676, pp 1497-1500, 4 p ; ref : 29 ref
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Chimiothérapie Facteur croissance épiderme Gène Géfitinib Mutation Poumon Récepteur facteur croissance Sensibilité résistance Traitement Tumeur maligne Appareil respiratoire pathologie
- Keyword (en)
- Chemotherapy Epidermal growth factor Gene Gefitinib Mutation Lung Growth factor receptor Sensitivity resistance Treatment Malignant tumor Respiratory disease
- Keyword (es)
- Quimioterapia Factor crecimiento epidermi Gen Gefitinib Mutación Pulmón Receptor factor crecimiento Sensibilidad resistencia Tratamiento Tumor maligno Aparato respiratorio patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15837414
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1099314 
https://dx.doi.org/10.1126/science.1099314
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