New antithrombotics with an indazole structure
- Author
- ALI KEMAL YILDIZ1 ; REHSE, Klaus1 ; STASCH, Johannes-Peter2 ; BISCHOFF, Erwin2
[1] Institut für Pharmazie, Freie Universität Berlin, Berlin, Germany
[2] Institute of Cardiovascular Research, Bayer AG, Wuppertal, Germany - Source
Archiv der Pharmazie (Weinheim). 2004, Vol 337, Num 6, pp 311-316, 6 p ; ref : 8 ref
- CODEN
- ARPMAS
- ISSN
- 0365-6233
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Wiley-VCH, Weinheim
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- YC-1 antithrombotic properties indazole derivates phosphodiesterase 5 soluble guanylate cylase
- Keyword (fr)
- 3',5'-Cyclic-GMP phosphodiesterase Aminoalcool Animal Anticoagulant Benzène dérivé Carboxamide Composé aromatique Composé bicyclique Hétérocycle azote In vitro In vivo Inhibiteur enzyme Inhibiteur thromboagrégation Isozyme Mécanisme action Rat Relation structure activité Synthèse chimique Voie orale Antithrombotique Ethanolamine dérivé Indazole-3-carboxamide(1-[2-fluorobenzyl]-N-[3-(2-hydroxyéthyl)propyl]) Enzyme Esterases Fluor Composé organique Hydrolases Mammalia Phosphoric diester hydrolases Rodentia Vertebrata
- Keyword (en)
- 3',5'-Cyclic-GMP phosphodiesterase Aminoalcohol Animal Anticoagulant Benzene derivatives Carboxamide Aromatic compound Bicyclic compound Nitrogen heterocycle In vitro In vivo Enzyme inhibitor Antiplatelet agent Isozyme Mechanism of action Rat Structure activity relation Chemical synthesis Oral administration Antithrombotic agent Enzyme Esterases Fluorine Organic compounds Hydrolases Mammalia Phosphoric diester hydrolases Rodentia Vertebrata
- Keyword (es)
- 3',5'-Cyclic-GMP phosphodiesterase Aminoalcohol Animal Anticoagulante Benceno derivado Carboxamida Compuesto aromático Compuesto bicíclico Heterociclo nitrógeno In vitro In vivo Inhibidor enzima Inhibidor tromboagregación Isozima Mecanismo acción Rata Relación estructura actividad Síntesis química Vía oral Antithrombotico Enzima Esterases Fluor Compuesto orgánico Hydrolases Mammalia Phosphoric diester hydrolases Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02G Blood. Blood coagulation. Reticuloendothelial system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15839288
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/ardp.200300832 
https://dx.doi.org/10.1002/ardp.200300832
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