Novel iodine-124 labeled EGFR inhibitors as potential PET agents for molecular imaging in cancer
- Author
- SHAUL, Mazal1 ; ABOURBEH, Galith1 2 ; JACOBSON, Orit1 ; ROZEN, Yulia1 ; LAKY, Desideriu1 ; LEVITZKI, Alexander2 ; MISHANI, Eyal1
[1] Department of Medical Biophysics and Nuclear Medicine, Hadassah Hebrew University, Hadassah Hospital, Jerusalem 91120, Israel
[2] Unit of Cellular Signaling, Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University, Jerusalem 91904, Israel - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 13, pp 3421-3429, 9 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Agent scintigraphique Aniline dérivé Carboxamide Carcinome épidermoïde Cellule tumorale Composé aromatique Composé bicyclique Facteur croissance épiderme Homme Hétérocycle azote In vitro Inhibiteur enzyme Inhibition Iode 124 Iode Isotope Lignée cellulaire Marquage isotopique Protein-tyrosine kinase Quinazoline dérivé Récepteur facteur croissance Synthèse chimique Transduction signal Acétamide(N-[4-(3-iodoanilino)quinazolin-6-yl]-méthoxy) Acétamide(chloro N-[4-(3-iodoanilino)quinazolin-6-yl]) But-2-énamide(4-diméthylamino N-[4-(3-iodoanilino)quinazolin-6-yl]) Lignée A431 Enzyme Transferases
- Keyword (en)
- Scintigraphic agent Aniline derivatives Carboxamide Squamous cell carcinoma Tumor cell Aromatic compound Bicyclic compound Epidermal growth factor Human Nitrogen heterocycle In vitro Enzyme inhibitor Inhibition Iodine 124 Iodine Isotopes Cell line Isotope labelling Protein-tyrosine kinase Quinazoline derivatives Growth factor receptor Chemical synthesis Signal transduction Enzyme Transferases
- Keyword (es)
- Agente centelleográfico Anilina derivado Carboxamida Carcinoma epidermoide Célula tumoral Compuesto aromático Compuesto bicíclico Factor crecimiento epidermi Hombre Heterociclo nitrógeno In vitro Inhibidor enzima Inhibición Iodo Isótopo Línea celular Marcación isotópica Protein-tyrosine kinase Receptor factor crecimiento Síntesis química Transducción señal Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02T Contrast media. Radiopharmaceuticals
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15859682
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.04.044 
https://dx.doi.org/10.1016/j.bmc.2004.04.044
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