Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives
- Author
- MÄNTYLÄ, Antti1 ; RAUTIO, Jarkko1 ; NEVALAINEN, Tapio1 ; VEPSÄLAINEN, Jouko2 ; JUVONEN, Risto3 ; KENDRICK, Howard4 ; GARNIER, Tracy4 ; CROFT, Simon L4 ; JÄRVINEN, Tomi1
[1] Department of Pharmaceutical Chemistry, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
[2] Department of Chemistry, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
[3] Department of Pharmacology and Toxicology, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
[4] Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, United Kingdom - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 13, pp 3497-3502, 6 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amastigote Animal Antiparasitaire Antiprotozoaire Buparvaquone Composé aromatique Composé bicyclique Foie In vitro Leishmania donovani Microsome Métabolisme Naphtoquinone dérivé Oxime Promédicament Rat Relation structure activité Synthèse chimique Kinetoplastida Mammalia Protozoa Rodentia Vertebrata
- Keyword (en)
- Amastigote Animal Parasiticide Antiprotozoal agent Buparvaquone Aromatic compound Bicyclic compound Liver In vitro Leishmania donovani Microsome Metabolism Naphthoquinone derivatives Oxime Prodrug Rat Structure activity relation Chemical synthesis Kinetoplastida Mammalia Protozoa Rodentia Vertebrata
- Keyword (es)
- Amastigota Animal Antiparasitario Antiprotozoario Buparvacuona Compuesto aromático Compuesto bicíclico Hígado In vitro Leishmania donovani Microsoma Metabolismo Oxima Promedicamento Rata Relación estructura actividad Síntesis química Kinetoplastida Mammalia Protozoa Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15859688
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.04.032 
https://dx.doi.org/10.1016/j.bmc.2004.04.032
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