Synthesis and antitumor activity of 20-O-linked nitrogen-based camptothecin ester derivatives
- Author
- WANG, Cun-Ying1 ; PAN, Xian-Dao2 ; LIU, Hong-Yan2 ; FU, Zhao-Di2 ; WEI, Xian-Yong1 ; YANG, Li-Xi3
[1] School of Chemical Engineering and Technology, China University of Mining and Technology, Xuzhou 221008, China
[2] Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
[3] CRadiation Biology Lab, California Pacific Medical Center, San Francisco, CA 94118, United States - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 13, pp 3657-3662, 6 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acylate Alcaloïde Alcool tertiaire Animal Anticancéreux Cellule tumorale Chimiothérapie Composé aromatique Composé pentacyclique Cytotoxicité Diéther Foie Homme Hétérocycle azote Hétérocycle oxygène azote In vitro In vivo Isoquinoléine dérivé Lactame Lactone Lignée cellulaire Pathologie expérimentale Pipérazine dérivé Relation structure activité Souris Synthèse chimique Traitement Tumeur maligne Voie intrapéritonéale Camptothécine(O-[3-(6,7-diméthoxy-1,2,3,4-tétrahydro-2-isoquinolyl)propionyl]) Appareil digestif pathologie Mammalia Rodentia Vertebrata
- Keyword (en)
- Acylate Alkaloid Tertiary alcohol Animal Antineoplastic agent Tumor cell Chemotherapy Aromatic compound Pentacyclic compound Cytotoxicity Diether Liver Human Nitrogen heterocycle Oxygen nitrogen heterocycle In vitro In vivo Isoquinoline derivatives Lactam Lactone Cell line Experimental disease Piperazine derivatives Structure activity relation Mouse Chemical synthesis Treatment Malignant tumor Intraperitoneal administration Digestive diseases Mammalia Rodentia Vertebrata
- Keyword (es)
- Acilato Alcaloide Alcohol terciario Animal Anticanceroso Célula tumoral Quimioterapia Compuesto aromático Compuesto pentacíclico Citotoxicidad Dieter Hígado Hombre Heterociclo nitrógeno Heterociclo oxígeno nitrógeno In vitro In vivo Isoquinoleína Lactamo Lactona Línea celular Patología experimental Piperazina derivado Relación estructura actividad Ratón Síntesis química Tratamiento Tumor maligno Vía intraperitoneal Aparato digestivo patología Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15859704
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.04.023 
https://dx.doi.org/10.1016/j.bmc.2004.04.023
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