Synthesis and anticancer activity evaluation of new 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethyl-quinoxaline 1,4-di-N-oxide derivatives
- Author
- ZARRANZ, Belén1 ; JASO, Andrés1 ; ALDANA, Ignacio1 ; MONGE, Antonio1
[1] Unidad en Investigación y Desarrollo de Medicamentos, Centro de Investigación en Farmacobiología Aplicada (CIFA), Universidad de Navarra, cl Irunlarrea s/n, 31080 Pamplona, Spain - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 13, pp 3711-3721, 11 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Cellule tumorale Composé aromatique Composé bicyclique Cytotoxicité Cétone Homme Hétérocycle azote In vitro Lignée cellulaire Nitrone Quinoxaline dérivé Relation structure activité Synthèse chimique Chlore Composé organique Fluor Composé organique
- Keyword (en)
- Antineoplastic agent Tumor cell Aromatic compound Bicyclic compound Cytotoxicity Ketone Human Nitrogen heterocycle In vitro Cell line Nitrone Quinoxaline derivatives Structure activity relation Chemical synthesis Chlorine Organic compounds Fluorine Organic compounds
- Keyword (es)
- Anticanceroso Célula tumoral Compuesto aromático Compuesto bicíclico Citotoxicidad Cetona Hombre Heterociclo nitrógeno In vitro Línea celular Nitrona Quinoxalina derivado Relación estructura actividad Síntesis química Cloro Compuesto orgánico Fluor Compuesto orgánico
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15859711
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.04.013 
https://dx.doi.org/10.1016/j.bmc.2004.04.013
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