Progesterone receptor ligand binding pocket flexibility: Crystal structures of the norethindrone and mometasone furoate complexes
- Author
- MADAUSS, Kevin P1 ; DENG, Su-Jun1 ; AUSTIN, Robert J. H1 ; LAMBERT, Millard H1 ; MCLAY, Iain1 ; PRITCHARD, John1 ; SHORT, Steven A1 ; STEWART, Eugene L1 ; UINGS, Ian J1 ; WILLIAMS, Shawn P1
[1] GlaxoSmithKline Inc., 5 Moore Drive, Research Triangle Park, North Carolina 27709, United States - Source
Journal of medicinal chemistry (Print). 2004, Vol 47, Num 13, pp 3381-3387, 7 p ; ref : 21 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antiinflammatoire Contraceptif Diffraction RX Fixation biologique Fixation ligand Interaction moléculaire Modèle moléculaire Modélisation Mométasone Noréthistérone Récepteur hormonal Récepteur progestérone Site fixation Structure cristalline Stéroïde Corticostéroïde Progestatif
- Keyword (en)
- Antiinflammatory agent Contraceptive X ray diffraction Biological fixation Ligand binding Molecular interaction Molecular model Modeling Mometasone Norethisterone Hormonal receptor Progesterone receptor Binding site Crystalline structure Steroid Corticosteroid Progestagen
- Keyword (es)
- Antiinflamatorio Anticonceptivo Difracción RX Fijación biológica Fijación ligando Interacción molecular Modelo molecular Modelización Mometasona Noretisterona Receptor hormonal Receptor progesterona Sitio fijación Estructura cristalina Esteroide Corticoesteroide Progestágeno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02O Hormones. Endocrine system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15860456
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm030640n 
https://dx.doi.org/10.1021/jm030640n
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