Synthesis and binding properties of novel selective 5-HT3 receptor ligands
- Author
- MODICA, Maria1 ; ROMEO, Giuseppe1 ; MATERIA, Luisa1 ; RUSSO, Filippo1 ; CAGNOTTO, Alfredo2 ; MENNINI, Tiziana2 ; GASPAR, Robert3 ; FALKAY, George3 ; FÜLÖP, Ferenc4
[1] Dipartimento di Scienze Farmaceutiche, Università di Catania, viale A. Doria 6, 95125 Catania, Italy
[2] Istituto di Ricerche Farmacologiche ' Mario Negri', via Eritrea 62, 20157 Milano, Italy
[3] Department of Pharmacodynamics and Biopharmacy, University of Szeged, POB 121, 6701 Szeged, Hungary
[4] Institute of Pharmaceutical Chemistry, University of Szeged, POB 121, 6701 Szeged, Hungary - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 14, pp 3891-3901, 11 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Affinité Animal Antagoniste Cobaye Composé bicyclique Composé tricyclique Contraction musculaire Encéphale Ester Hétérocycle soufre azote Iléon Intestin Lactame Muscle lisse Pipérazine dérivé Pyrimidine dérivé Rat Relation structure activité Récepteur sérotoninergique 5-HT3 Synthèse chimique Sélectivité Cyclopenta[4,5]thiéno[2,3-d]pyrimidine dérivé Cyclopentathiénopyrimidine Thiéno[2,3-d]pyrimidine dérivé Thiénopyrimidine Mammalia Rodentia Système nerveux central Vertebrata
- Keyword (en)
- Affinity Animal Antagonist Guinea pig Bicyclic compound Tricyclic compound Muscle contraction Encephalon Ester Sulfur nitrogen heterocycle Ileum Gut Lactam Smooth muscle Piperazine derivatives Pyrimidine derivatives Rat Structure activity relation 5-HT3 Serotonine receptor Chemical synthesis Selectivity Mammalia Rodentia Central nervous system Vertebrata
- Keyword (es)
- Afinidad Animal Antagonista Cobayo Compuesto bicíclico Compuesto tricíclico Contracción muscular Encéfalo Ester Heterociclo azufre nitrógeno Ileon Intestino Lactamo Músculo liso Piperazina derivado Pirimidina derivado Rata Relación estructura actividad Receptor serotoninérgico 5-HT3 Síntesis química Selectividad Mammalia Rodentia Sistema nervioso central Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15888779
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.04.043 
https://dx.doi.org/10.1016/j.bmc.2004.04.043
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