Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents
- Author
- ISMAIL, Mohamed A; BRUN, Reto; WENZLER, Tanja; TANIOUS, Farial A; WILSON, W. David; BOYKIN, David W
Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30303-3083, United States
Swiss Tropical Institute, Basel, 4002, Switzerland - Source
Journal of medicinal chemistry (Print). 2004, Vol 47, Num 14, pp 3658-3664, 7 p ; ref : 29 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amidine Amidoxime Animal Antiparasitaire Antiprotozoaire Benzène dérivé Chimiothérapie Composé bicyclique Furane dérivé Hétérocycle azote angulaire In vitro In vivo Promédicament Relation structure activité Souris Synthèse chimique Traitement Trypanosoma rhodesiense Trypanosomiase Voie intrapéritonéale Voie orale Benzamidine dérivé Imidazo[1,2-a]pyridine-6-carboxamidine dérivé Imidazopyridine Infection Kinetoplastida Mammalia Parasitose Protozoa Protozoose Rodentia Vertebrata
- Keyword (en)
- Amidine Amidoxime Animal Parasiticide Antiprotozoal agent Benzene derivatives Chemotherapy Bicyclic compound Furan derivatives Angular nitrogen heterocycle In vitro In vivo Prodrug Structure activity relation Mouse Chemical synthesis Treatment Trypanosoma rhodesiense Trypanosomiasis Intraperitoneal administration Oral administration Infection Kinetoplastida Mammalia Parasitosis Protozoa Protozoal disease Rodentia Vertebrata
- Keyword (es)
- Amidina Amidoxima Animal Antiparasitario Antiprotozoario Benceno derivado Quimioterapia Compuesto bicíclico Furano derivado Heterociclo nitrógeno angular In vitro In vivo Promedicamento Relación estructura actividad Ratón Síntesis química Tratamiento Trypanosoma rhodesiense Tripanosomiasis Vía intraperitoneal Vía oral Infección Kinetoplastida Mammalia Parasitosis Protozoa Protozoosis Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15913888
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm0400092 
https://dx.doi.org/10.1021/jm0400092
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