Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
- Author
- LIN YANG1 ; DAN, Han C1 ; SEBTI, Said M1 ; CHENG, Jin Q1 ; MEI SUN1 ; QIYUAN LIU1 ; SUN, Xia-Meng1 ; FELDMAN, Richard I2 ; HAMILTON, Andrew D3 ; POLOKOFF, Mark2 ; NICOSIA, Santo V1 ; HERLYN, Meenhard4
[1] Department of Pathology and Interdisciplinary Oncology, University of South Florida College of Medicine, H. Lee Moffitt Cancer Center, Tampa, Florida, United States
[2] Berlex Biosciences, Richmond, California, United States
[3] Department of Chemistry, Yale University, New Haven, Connecticut, United States
[4] The Wistar Institute, Philadelphia, Pennsylvania, United States - Source
Cancer research (Baltimore). 2004, Vol 64, Num 13, pp 4394-4399, 6 p ; ref : 20 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Anticancéreux Cellule tumorale In vitro Inhibiteur enzyme Protein kinase Surexpression génique Transduction signal Tumeur maligne Protein kinase B Enzyme Transferases
- Keyword (en)
- Biological activity Antineoplastic agent Tumor cell In vitro Enzyme inhibitor Protein kinase Gene overexpression Signal transduction Malignant tumor Enzyme Transferases
- Keyword (es)
- Actividad biológica Anticanceroso Célula tumoral In vitro Inhibidor enzima Protein kinase Sobreexpressión genética Transducción señal Tumor maligno Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15918485
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/0008-5472.CAN-04-0343 
https://dx.doi.org/10.1158/0008-5472.CAN-04-0343
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