Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies
- Author
- MILLER, Michael L1 ; ROLLER, Elizabeth E1 ; XINYAUN WU2 ; LEECE, Barbara A1 ; GOLDMACHER, Victor S1 ; CHARM, Ravi V. J1 ; OJIMA, Iwao2
[1] ImmunoGen, Inc., 128 Sidney Street, Cambridge, MA 02139, United States
[2] Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794-3400, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 15, pp 4079-4082, 4 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Anticancéreux Anticorps monoclonal Disulfure organique Diterpène Immunoconjugué Médicament ciblé Synthèse chimique Taxane dérivé Terpénoïde Tumeur Bras espaceur Taxoïde
- Keyword (en)
- Biological activity Antineoplastic agent Monoclonal antibody Organic disulfide Diterpene Immunoconjugate Targeted drug Chemical synthesis Taxane derivatives Terpenoid Tumor Spacer arm
- Keyword (es)
- Actividad biológica Anticanceroso Anticuerpo monoclonal Disulfuro orgánico Diterpeno Inmunoconjugado Medicamento dirigido Síntesis química Taxane derivado Terpenoide Tumor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15919334
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2004.05.027 
https://dx.doi.org/10.1016/j.bmcl.2004.05.027
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