Synthesis and biological evaluation of nonpeptide mimetics of ω-conotoxin GVIA
- Author
- BAELL, Jonathan B1 2 ; DUGGAN, Peter J3 ; FORSYTH, Stewart A1 ; LEWIS, Richard J4 ; PHEI LOK, Y3 ; SCHROEDER, Christina I4
[1] Biomolecular Research Institute, 343 Royal Parade, Parkville, Vic 3052, Australia
[2] Structural Biology-Chemistry Group, The Walter and Eliza Hall, Institute of Medical Research, Biotechnology Centre, 4 Research Avenue, La Trobe R & D Park, Bundoora, Vic 3086, Australia
[3] School of Chemistry, Monash University, Clayton, Vic 3800, Australia
[4] Institute of Molecular Bioscience, The University of Queensland, St. Lucia, Qld 4072, Australia - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 15, pp 4025-4037, 13 p ; ref : 44 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Affinité Amine Animal Benzamide dérivé Benzothiazole dérivé Calcium Canal ionique Chaîne latérale Composé non peptide Composé peptidomimétique Fixation biologique Phénols Rat Synthèse chimique Système nerveux central Sélectivité Toxique Venin Canal calcium Conotoxine Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Affinity Amine Animal Benzamide derivatives Benzothiazole derivatives Calcium Ionic channel Side chain Non peptide compound Peptidomimetic compound Biological fixation Phenols Rat Chemical synthesis Central nervous system Selectivity Poison Venom Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Afinidad Amina Animal Benzamida derivado Benzotiazol derivado Calcio Canal iónico Cadena lateral Compuesto no péptido Compuesto peptidomimético Fijación biológica Fenoles Rata Síntesis química Sistema nervioso central Selectividad Tóxico Veneno Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25D Central nervous system / 002A25D03 Electrophysiology
- Discipline
- Vertebrates : nervous system and sense organs
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15950828
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.05.040 
https://dx.doi.org/10.1016/j.bmc.2004.05.040
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