Selective inhibition of STAT3 induces apoptosis and G1 cell cycle arrest in ALK-positive anaplastic large cell lymphoma
- Author
- AMIN, Hesham M1 ; MCDONNELL, Timothy J2 ; MEDEIROS, L. Jeffrey1 ; LAI, Raymond1 ; MA, Yupo1 ; QUAN LIN1 ; FUJIO, Yasushi3 ; KUNISADA, Keita3 ; LEVENTAKI, Vasiliki1 ; DAS, Pamela1 ; RASSIDAKIS, George Z1 ; CUTLER, Cathy1
[1] Department of Hematopathology, Box 72, The University of Texas MD Anderson Cancer Center, 1515 Holcomhe Boulevard, Houston, TX 77030, United States
[2] Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center., Houston, TX 77030, United States
[3] Department of Molecular Medicine, Graduate School of Medicine, Osaka, Japan - Source
Oncogene (Basingstoke). 2004, Vol 23, Num 32, pp 5426-5434, 9 p ; ref : 47 ref
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- NPM-ALK STAT3 adenoviral vectors anaplastic large cell lymphoma apoptosis cell cycle
- Keyword (fr)
- Adenoviridae Apoptose Carcinogenèse Cycle cellulaire Facteur transcription STAT3 Gène hybride Inhibiteur Inhibition Lymphome anaplasique grande cellule Ki1 positive Lymphome grande cellule Thérapie génique Translocation chromosomique Gène ALK Gène npm T(2;5) Aberration chromosomique Chromosome anormal Hémopathie maligne Lymphome non hodgkinien Lymphoprolifératif syndrome Virus
- Keyword (en)
- Adenoviridae Apoptosis Carcinogenesis Cell cycle Transcription factor STAT3 Hybrid gene Inhibitor Inhibition Ki1 positive large cell anaplastic lymphoma Large cell lymphoma Gene therapy Chromosome translocation Chromosomal aberration Abnormal chromosome Malignant hemopathy Non Hodgkin lymphoma Lymphoproliferative syndrome Virus
- Keyword (es)
- Adenoviridae Apoptosis Carcinogénesis Ciclo celular Factor transcripción STAT3 Gen híbrido Inhibidor Inhibición Linfoma anaplásico célula grande Ki1 positiva Linfoma célula grande Terapia génica Translocación cromosómica Aberración cromosómica Cromosoma anormal Hemopatía maligna Linfoma no Hodgkin Linfoproliferativo síndrome Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15954241
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1207703 
https://dx.doi.org/10.1038/sj.onc.1207703
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