Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity
- Author
- URBAN, Milan1 ; SAREK, Jan1 ; KLINOT, Jiri1 ; KORINKOVA, Gabriela2 ; HAJDUCH, Marian2
[1] Department of Organic and Nuclear Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, 128 43 Prague, Czech Republic
[2] Laboratory of Experimental Medicine, Department of Pediatrics, Faculty of Medicine, Palacky University and Faculty Hospital in Olomouc, Puskinova 6, 775 20 Olomouc, Czech Republic - Source
Journal of natural products (Print). 2004, Vol 67, Num 7, pp 1100-1105, 6 p ; ref : 22 ref
- CODEN
- JNPRDF
- ISSN
- 0163-3864
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
/
American Society of Pharmacognosy, Glendale, AZ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acylate Alcool primaire Anhydride organique Anticancéreux Cellule tumorale Composé pentacyclique Composé tétracyclique Cytotoxicité Homme Hétérocycle oxygène In vitro Lignée cellulaire Relation structure activité Synthèse chimique Terpénoïde Triterpène 2,3-Secolup-20(29)-ène-2,3,28-trioïque acide dérivé Bétulinique acide Lupa-1,20(29)-dién-28-oïque acide dérivé Lupane dérivé
- Keyword (en)
- Acylate Primary alcohol Organic anhydride Antineoplastic agent Tumor cell Pentacyclic compound Tetracyclic compound Cytotoxicity Human Oxygen heterocycle In vitro Cell line Structure activity relation Chemical synthesis Terpenoid Triterpene
- Keyword (es)
- Acilato Alcohol primario Anhídrido orgánico Anticanceroso Célula tumoral Compuesto pentacíclico Compuesto tetracíclico Citotoxicidad Hombre Heterociclo oxígeno In vitro Línea celular Relación estructura actividad Síntesis química Terpenoide Triterpeno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15986268
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/np049938m 
https://dx.doi.org/10.1021/np049938m
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