Synthesis and structural-activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agents
- Author
- TRAN, Tuan P1 ; ELLSWORTH, Edmund L1 ; STIER, Michael A1 ; DOMAGALA, John M1 ; SHOWALTER, H. D1 ; GRACHECK, Stephen J2 ; SHAPIRO, Martin A2 ; JOANNIDES, Themis E2 ; SINGH, Rajeshwar3
[1] Department of Chemistry, Pfizer Glohal Research and Development, Ann Arbor Laboratories, 2800 Plymouth Road, Ann Arbor, MI 48105, United States
[2] Department of Antibacterial Pharmacology, Pfizer Global Research and Development, Ann Arbor Laboratories, 2800 Plymouth Road, Ann Arbor, MI 48105, United States
[3] NAEJA Pharmaceuticals, 4290-91A Street, Edmonton, Alta., T6E 5V2, Canada - Source
Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 17, pp 4405-4409, 5 p ; ref : 23 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antibactérien DNA topoisomerase (ATP-hydrolysing) Escherichia coli In vitro Inhibiteur enzyme Quinazoline dérivé Synthèse chimique Bactérie Enterobacteriaceae Enzyme Isomerases
- Keyword (en)
- Biological activity Antibacterial agent DNA topoisomerase (ATP-hydrolysing) Escherichia coli In vitro Enzyme inhibitor Quinazoline derivatives Chemical synthesis Bacteria Enterobacteriaceae Enzyme Isomerases
- Keyword (es)
- Actividad biológica Antibacteriano DNA topoisomerase (ATP-hydrolysing) Escherichia coli In vitro Inhibidor enzima Síntesis química Bacteria Enterobacteriaceae Enzima Isomerases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16002521
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2004.06.063 
https://dx.doi.org/10.1016/j.bmcl.2004.06.063
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