CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas
- Author
- PAZ, Maria F1 ; YAYA-TUR, Ricard2 ; SANCHEZ-CESPEDES, Montserrat10 ; GARCIA-VILLANUEVA, Mercedes10 ; ARRIBAS, Leoncio2 ; ESTELLER, Manel1 ; ROJAS-MARCOS, Inigo3 ; REYNES, Gaspar4 ; POLLAN, Marina5 ; AGUIRRE-CRUZ, Lucinda3 6 ; GARCIA-LOPEZ, Jose Luis7 ; PIQUER, Jose8 ; SAFONT, Maria-Jose8 ; BALANA, Carmen9
[1] Cancer Epigenetics Laboratory, Spanish National Cancer Centre (CNIO), Madrid, Spain
[2] Medical Oncology and Radiotherapy Departments, Instituto Valenciano de Oncologia, Valencia, Spain
[3] Neurology Department, Hôpital Pitié-Salpetrière, INSERM U495, Paris, France
[4] Medical Oncology Department, Hospital Universitario La Fe, Valencia, Spain
[5] Cancer Epidemiology Unit, Spanish National Center for Epidemiology, Carlos III Institute of Health, Madrid, Spain
[6] National Institute of Neurology and Neurosurgery, Mexico DF, Mexico
[7] Medical Oncology and Pathology Departments, Hospital Ramón y Cajal, Madrid, Spain
[8] Neurosurgery and Medical Oncology Departments, Hospital de la Ribera, Alzira, Spain
[9] Medical Oncology Department, Hospital Germans Tries i Pujol, Badalona, Catalonia, Spain
[10] Molecular Pathology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain - Source
Clinical cancer research. 2004, Vol 10, Num 15, pp 4933-4938, 6 p ; ref : 48 ref
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux DNA Enzyme Gliome Methyltransferases Méthylation Primaire Séquence riche GC Témozolomide Réparation DNA Agent alkylant Système nerveux central pathologie Système nerveux pathologie Transferases Tumeur
- Keyword (en)
- Antineoplastic agent DNA Enzyme Glioma Methyltransferases Methylation Primary GC rich sequence Temozolomide DNA repair Alkylating agent Central nervous system disease Nervous system diseases Transferases Tumor
- Keyword (es)
- Anticanceroso DNA Enzima Glioma Methyltransferases Metilación Primario Secuencia rica GC Temozolomida Agente alquilante Sistema nervosio central patología Sistema nervioso patología Transferases Tumor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16014607
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-04-0392 
https://dx.doi.org/10.1158/1078-0432.CCR-04-0392
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