Synthesis, acute toxicities, and antitumor effects of novel 9-substituted β-carboline derivatives
- Author
- RIHUI CAO1 ; QI CHEN1 ; XUERUI HOU1 ; HONGSHENG CHEN1 ; HUAJI GUAN1 ; YAN MA1 ; WENLIE PENG1 ; ANLONG XU1
[1] Department of Biochemistry and Center for Biopharmaceutical Research, College of Life Sciences, Sun Yat-sen (Zhongshan) University, 135 Xin Gang Xi Road, Guangzhou 510275, China - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 17, pp 4613-4623, 11 p ; ref : 32 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aigu Alcaloïde Animal Anticancéreux Cellule tumorale Chimiothérapie Composé aromatique Composé tricyclique Cytotoxicité Hétérocycle azote In vitro In vivo Lignée cellulaire Neurotoxicité Relation structure activité Sarcome 180 Souris Synthèse chimique Système nerveux Toxicité Traitement Tumeur Lewis Tumeur maligne Voie intrapéritonéale Pyrido[3,4-b]indole dérivé Pyridoindole β-Carboline-3-carboxylique acide(9-butyl) Mammalia Rodentia Vertebrata
- Keyword (en)
- Acute Alkaloid Animal Antineoplastic agent Tumor cell Chemotherapy Aromatic compound Tricyclic compound Cytotoxicity Nitrogen heterocycle In vitro In vivo Cell line Neurotoxicity Structure activity relation Sarcoma 180 Mouse Chemical synthesis Nervous system Toxicity Treatment Lewis lung carcinoma Malignant tumor Intraperitoneal administration Mammalia Rodentia Vertebrata
- Keyword (es)
- Agudo Alcaloide Animal Anticanceroso Célula tumoral Quimioterapia Compuesto aromático Compuesto tricíclico Citotoxicidad Heterociclo nitrógeno In vitro In vivo Línea celular Neurotoxicidad Relación estructura actividad Sarcoma 180 Ratón Síntesis química Sistema nervioso Toxicidad Tratamiento Tumor Lewis Tumor maligno Vía intraperitoneal Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16017800
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.06.038 
https://dx.doi.org/10.1016/j.bmc.2004.06.038
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