QSAR analysis of some fused pyrazoles as selective cyclooxygenase-2 inhibitors: A Hansch approach
- Author
- PRASANNA, Sivaprakasam1 ; MANIVANNAN, Elangovan1 ; SUBASH CHANDRA CHATURVEDI1
[1] School of Pharmacy, DAVV, Indore-452017, Madhya Pradesh, India - Source
Archiv der Pharmazie (Weinheim). 2004, Vol 337, Num 8, pp 440-444, 5 p ; ref : 17 ref
- CODEN
- ARPMAS
- ISSN
- 0365-6233
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Wiley-VCH, Weinheim
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- COX-1 COX-2 Hydrophobicity QSAR Selectivity
- Keyword (fr)
- Antiinflammatoire non stéroïde Composé aromatique Composé bicyclique Composé tricyclique Cyclooxygenase 2 Hétérocycle azote angulaire Hétérocycle oxygène azote Hétérocycle soufre azote In vitro Inhibiteur cyclooxygenase 2 Inhibiteur enzyme Lipophilie Modélisation Propriété physicochimique Prédiction Relation propriété physicochimique activité Relation structure activité Relation structure propriété Sélectivité QSAR Enzyme Oxidoreductases
- Keyword (en)
- Non steroidal antiinflammatory agent Aromatic compound Bicyclic compound Tricyclic compound Cyclooxygenase 2 Angular nitrogen heterocycle Oxygen nitrogen heterocycle Sulfur nitrogen heterocycle In vitro Cyclooxygenase 2 inhibitor Enzyme inhibitor Lipophilicity Modeling Physicochemical properties Prediction Physicochemical properties activity relationship Structure activity relation Property structure relationship Selectivity Enzyme Oxidoreductases
- Keyword (es)
- Antiinflamatorio no esteroide Compuesto aromático Compuesto bicíclico Compuesto tricíclico Cyclooxygenase 2 Heterociclo nitrógeno angular Heterociclo oxígeno nitrógeno Heterociclo azufre nitrógeno In vitro Inhibidor cyclooxygenase 2 Inhibidor enzima Lipofilia Modelización Propiedad fisicoquímica Predicción Relación propiedad fisicoquímica actividad Relación estructura actividad Relación estructura propiedad Selectividad Enzima Oxidoreductases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16019811
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/ardp.200400887 
https://dx.doi.org/10.1002/ardp.200400887
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