Pyrimidine methyl anilines: selective potentiators for the metabotropic glutamate 2 receptor
- Author
- HU, Essa1 ; CHUA, Peter C1 ; TEHRANI, Lida1 ; NAGASAWA, Johnny Y1 ; PINKERTON, Anthony B1 ; ROWE, Blake A2 ; VERNIER, Jean-Michel1 ; HUTCHINSON, John H1 ; COSFORD, Nicholas D. P1
[1] Department of Medicinal Chemistry, Merck Research Laboratories, San Diego, CA 92121, United States
[2] Department of Molecular Profiling, Merck Research Laboratories, San Diego, CA 92121, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 20, pp 5071-5074, 4 p ; ref : 8 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amine aromatique Aniline dérivé Pyrimidine dérivé Relation structure activité Récepteur glutamate mglu2 Récepteur glutamate Récepteur métabotropique Synthèse chimique Sélectivité
- Keyword (en)
- Aromatic amine Aniline derivatives Pyrimidine derivatives Structure activity relation mglu2 glutamate receptor Glutamate receptor Metabotropic receptor Chemical synthesis Selectivity
- Keyword (es)
- Amina aromática Anilina derivado Pirimidina derivado Relación estructura actividad Receptor glutamato mglu2 Receptor glutámato Receptor metabotropico Síntesis química Selectividad
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09E Glutamatergic system (aspartate and other excitatory aminoacids)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16119649
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2004.07.079 
https://dx.doi.org/10.1016/j.bmcl.2004.07.079
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