Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation
- Author
- PHAOSIRI, Chanokporn1 ; PROTEAU, Philip J1
[1] College of Pharmacy, Pharmacy Building. Rm. 203, Oregon State University, Corvallis, OR 97331-3507, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 21, pp 5309-5312, 4 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Carboxamide Composé aliphatique Cétol Cétone Cétose Hydroxyamide In vitro Inhibiteur enzyme Oxidoreductases Phosphate organique Phosphonique acide Protéine recombinante Relation structure activité Substrat Synechocystis Synthèse chimique 1-Deoxy-D-xylulose 5-phosphate reductoisomerase Bactérie Cyanobacteria Enzyme Phosphore Composé organique
- Keyword (en)
- Carboxamide Aliphatic compound Ketol Ketone Ketose Hydroxyamide In vitro Enzyme inhibitor Oxidoreductases Organic phosphate Phosphonic acids Recombinant protein Structure activity relation Substrate Synechocystis Chemical synthesis Bacteria Cyanobacteria Enzyme Phosphorus Organic compounds
- Keyword (es)
- Carboxamida Compuesto alifático Cetol Cetona Cetosa Hidroxiamida In vitro Inhibidor enzima Oxidoreductases Fosfato orgánico Proteína recombinante Relación estructura actividad Substrato Synechocystis Síntesis química Bacteria Cyanobacteria Enzima Fósforo Compuesto orgánico
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E02 Oxidoreductases
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- Analytical, structural and metabolic biochemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16148948
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2004.08.023 
https://dx.doi.org/10.1016/j.bmcl.2004.08.023
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