Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase itch
- Author
- GAO, Min1 ; LABUDA, Tord1 2 ; YING XIA1 ; GALLAGHER, Ewen1 ; DEYU FANG3 ; LIU, Yun-Cai3 ; KARIN, Michael1
[1] Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500, Gilman Drive, La Jolla, CA 92093-0723, United States
[2] Department of Medical Microbiology and immunology and Institute of Molecular Biology, University of Copenhagen, 2200 Copenhagen N, Denmark
[3] Division of Cell Biology, La jella Institute for Allergy and Immunology, San Diego, CA 92121, United States - Source
Science (Washington, D.C.). 2004, Vol 306, Num 5694, pp 271-275, 5 p
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Cytokine Expression génique Facteur transcription Lymphocyte Th2 Phosphorylation Protein kinase Protéolyse Régulation Ubiquitin-protein ligase Protéine JNK Protéine Jun Carbon-nitrogen ligases Enzyme Ligases Transferases
- Keyword (en)
- Cytokine Gene expression Transcription factor Th2 lymphocyte Phosphorylation Protein kinase Proteolysis Regulation(control) Ubiquitin-protein ligase Carbon-nitrogen ligases Enzyme Ligases Transferases
- Keyword (es)
- Citoquina Expresión genética Factor transcripción Linfocito Th2 Fosforilación Protein kinase Proteolisis Regulación Ubiquitin-protein ligase Carbon-nitrogen ligases Enzima Ligases Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05C Virology / 002A05C09 Techniques used in virology
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16190181
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1099414 
https://dx.doi.org/10.1126/science.1099414
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