Subtype selective substrates for histone deacetylases
- Author
- HELTWEG, Birgit1 ; DEQUIEDT, Franck2 ; MARSHALL, Brett L3 ; BRAUCH, Carsten1 ; YOSHIDA, Minoru4 ; NISHINO, Norikazu5 ; VERDIN, Eric3 ; JUNG, Manfred1
[1] Department of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität Münster, Hittorfstrasse 58-62, 48149 Münster, Germany
[2] Molecular and Cellular Biology Unit, FUSAGx, Gembloux 5030, Belgium
[3] Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141-9100, United States
[4] Chemical Genetics Laboratory, RIKEN, Hirosawa 2-1, Wako-shi, Saitama 351-0198, Japan
[5] Department of Applied Chemistry, Kyushu Institute of Technology, Tabata-ku, Kitakyushu-shi 804-8550, Japan - Source
Journal of medicinal chemistry (Print). 2004, Vol 47, Num 21, pp 5235-5243, 9 p ; ref : 35 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aminoamide Coumarine dérivé Hydrolases In vitro Lactone Relation structure activité Substrat Synthèse chimique Sélectivité α-Aminoacide Histone deacetylase Lysinamide(N6-acétyl-Nα-[benzyloxycarbonyl]-N-[4-méthyl-2-oxo-1-benzopyran-7-yl]) Lysinamide(N6-acétyl-Nα-[t-butoxycarbonyl]-N-[4-méthyl-2-oxo-1-benzopyran-7-yl]) Enzyme
- Keyword (en)
- Aminoamide Coumarine derivatives Hydrolases In vitro Lactone Structure activity relation Substrate Chemical synthesis Selectivity α-Aminoacid Enzyme
- Keyword (es)
- Aminoamida Hydrolases In vitro Lactona Relación estructura actividad Substrato Síntesis química Selectividad α-Aminoácido Enzima
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E04 Hydrolases
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- Analytical, structural and metabolic biochemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16200658
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm0497592 
https://dx.doi.org/10.1021/jm0497592
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