Synthesis and evaluation of pyridazinylpiperazines as vanilloid receptor 1 antagonists
- Author
- TAFESSE, Laykea1 ; QUN SUN1 ; SCHMID, Lori1 ; VALENZANO, Kenneth J1 ; ROTSHTEYN, Yakov1 ; XIN SU1 ; KYLE, Donald J1
[1] Discovery Research, Purdue Pharma L.P., 6 Cedar, Brook Drive, Cranbury, NJ 08512, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 22, pp 5513-5519, 7 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antagoniste Carboxamide Chimiothèque Chlore composé organique Embryon Homme Lignée cellulaire Pipérazine dérivé Pyridine dérivé Rein Récepteur vanilloïde VR1 Récepteur vanilloïde Synthèse chimique Lignée HEK293
- Keyword (en)
- Biological activity Antagonist Carboxamide Chemical compound library Organic chlorine compounds Embryo Human Cell line Piperazine derivatives Pyridine derivatives Kidney VR1 vanilloid receptor Vanilloid receptor Chemical synthesis
- Keyword (es)
- Actividad biológica Antagonista Carboxamida Quimioteca Embrión Hombre Línea celular Piperazina derivado Piridina derivado Riñón Receptor vaniloide VR1 Receptor vaniloide Síntesis química
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16202557
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2004.09.010 
https://dx.doi.org/10.1016/j.bmcl.2004.09.010
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