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Syntheses and bioactivities of macrocyclic paclitaxel bis-lactones

Author
CHANGHUI LIU1 ; SCHILLING, Jennifer K1 ; RAVINDRA, Rudravajhala2 ; BANE, Susan2 ; KINGSTON, David G. I1
[1] Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, United States
[2] Department of Chemistry, State University of New York, Binghamton, NY 13902, United States
Source

Bioorganic & medicinal chemistry. 2004, Vol 12, Num 23, pp 6147-6161, 15 p

ISSN
0968-0896
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier Science, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Anticancéreux Antimitotique Antitubuline Conformation Cytotoxicité Diterpène In vitro Lactone Macrocycle Modèle Paclitaxel Relation structure activité Synthèse chimique Taxane dérivé Terpénoïde Lignée A2780 Taxoïde
Keyword (en)
Antineoplastic agent Antimitotic Antitubulin Conformation Cytotoxicity Diterpene In vitro Lactone Macrocycle Models Paclitaxel Structure activity relation Chemical synthesis Taxane derivatives Terpenoid
Keyword (es)
Anticanceroso Antimitótico Antitubulina Conformación Citotoxicidad Diterpeno In vitro Lactona Macrociclo Modelo Paclitaxel Relación estructura actividad Síntesis química Taxane derivado Terpenoide
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16223288

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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