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Synthesis and structure-activity correlations of the cytotoxic bifunctional 1,4-diamidoanthraquinone derivatives

Author
HUANG, Hsu-Shan1 ; CHIU, Hui-Fen2 ; LEE, An-Long1 ; GUO, Ching-Long1 ; YUAN, Chun-Lung1
[1] School of Pharmacy, National Defense Medical Center, PO Box 90048-508, Neihu 114 Taipei, Taiwan, Province of China
[2] Department of Pharmacology, Kaohsiung Medical University, Kaohsiung, Taiwan, Province of China
Source

Bioorganic & medicinal chemistry. 2004, Vol 12, Num 23, pp 6163-6170, 8 p

ISSN
0968-0896
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier Science, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Animal Anthraquinone dérivé Anticancéreux Carboxamide Cellule gliale Cytotoxicité Doxorubicine Homme Hépatocyte In vitro Lignée cellulaire Mitoxantrone Nucleotidyltransferases Quinone Rat Relation structure activité Synthèse chimique Telomerase Anthraquinone(1,4-bis[acylamino]) Anthraquinone(1,4-bis[aroylamino]) Lignée C6 Lignée HEPG2 Enzyme Mammalia Rodentia Transferases Vertebrata
Keyword (en)
Animal Anthraquinone derivatives Antineoplastic agent Carboxamide Glial cell Cytotoxicity Doxorubicin Human Hepatocyte In vitro Cell line Mitoxantrone Nucleotidyltransferases Quinone Rat Structure activity relation Chemical synthesis Telomerase Enzyme Mammalia Rodentia Transferases Vertebrata
Keyword (es)
Animal Antraquinona derivado Anticanceroso Carboxamida Célula glial Citotoxicidad Doxorubicina Hombre Hepatocito In vitro Línea celular Mitoxantrona Nucleotidyltransferases Quinona Rata Relación estructura actividad Síntesis química Telomerase Enzima Mammalia Rodentia Transferases Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous

Discipline
General pharmacology Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16223289

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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