Synthesis and topoisomerase I inhibitory properties of luotonin A analogues
- Author
- CAGIR, Ali1 ; EISENHAUER, Brian M1 ; GAO, Rong1 ; THOMAS, Shannon J1 ; HECHT, Sidney M1
[1] Department of Chemistry and Department of Biology, University of Virginia, Charlottesville, VA 22901, United States - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 23, pp 6287-6299, 13 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Alcaloïde Clivage Composé aromatique Composé pentacyclique Cytotoxicité DNA topoisomerase DNA Hétérocycle azote angulaire In vitro Levure Relation structure activité Scission Synthèse chimique Luotonin dérivé Quino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11-one dérivé Quinopyrroloquinazoline Enzyme Isomerases
- Keyword (en)
- Alkaloid Cleavage Aromatic compound Pentacyclic compound Cytotoxicity DNA topoisomerase DNA Angular nitrogen heterocycle In vitro Yeast Structure activity relation Scission Chemical synthesis Enzyme Isomerases
- Keyword (es)
- Alcaloide Clivaje Compuesto aromático Compuesto pentacíclico Citotoxicidad DNA topoisomerase DNA Heterociclo nitrógeno angular In vitro Levadura Relación estructura actividad Escisión Síntesis química Enzima Isomerases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16223300
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.08.052 
https://dx.doi.org/10.1016/j.bmc.2004.08.052
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