Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone
- Author
- JOHNSON, Timothy E1 ; XIAOHUA ZHANG2 ; BLEICHER, Kimberly B1 ; DYSART, Gary1 ; LOUGHLIN, Amy F1 ; SCHAEFER, William H1 ; UMBENHAUER, Diane R1
[1] Department of Safety Assessment, Merck Research Laboratories, West Point, PA 19486, United States
[2] Department of Biometrics Research, Merck Research Laboratories, West Point, PA 19486, United States - Source
Toxicology and applied pharmacology. 2004, Vol 200, Num 3, pp 237-250, 14 p ; ref : 1 p.3/4
- CODEN
- TXAPA9
- ISSN
- 0041-008X
- Scientific domain
- Pharmacology drugs; Toxicology
- Publisher
- Elsevier, San Diego, CA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Geranylgeranylation Myotoxicity Myotube Statin
- Keyword (fr)
- Animal Apoptose Homme Mort cellulaire Myotube Protéine Rat Statine dérivé Ubiquinone Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Apoptosis Human Cell death Myotube Protein Rat Statin derivative Ubiquinone Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Apoptosis Hombre Muerte celular Miotubo Proteína Rata Statina derivado Ubiquinona Mammalia Rodentia Vertebrata
- Classification
- Discipline
- Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16258882
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.taap.2004.04.010 
https://dx.doi.org/10.1016/j.taap.2004.04.010
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