Synthesis and biological evaluation of new 1,5-diazaanthraquinones with cytotoxic activity
- Author
- MANZANARO, Sonia1 ; VICENT, Maria Jesus1 ; MARTIN, Maria Jesus1 ; SALVADOR-TORMO, Nélida1 ; PEREZ, José Maria2 ; DEL MAR BLANCO, Maria2 ; AVENDANO, Carmen2 ; MENENDEZ, José Carlos2 ; DE LA FUENTE, Jesus Angel1
[1] Instituto Biomar, S.A., Poligono Industrial, Edificio CEEI, 24231 Onzonilla, León, Spain
[2] Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Unirersidad Complutense, 28040 Madrid, Spain - Source
Bioorganic & medicinal chemistry. 2004, Vol 12, Num 24, pp 6505-6515, 11 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Addition Diels Alder Anticancéreux Carcinome Cellule tumorale Composé aromatique Composé tricyclique Cytotoxicité Glande mammaire Glioblastome Halogène composé organique Homme Hétérocycle azote In vitro Lignée cellulaire Mitoxantrone Quinone Relation structure activité Synthèse chimique Lignée SKBr3 Lignée T98G Pyrido[2,3-g]quinoléine-5,10-dione(9-chloro-4-méthyl) Pyridoquinoléine Système nerveux central pathologie Système nerveux pathologie
- Keyword (en)
- Diels Alder addition Antineoplastic agent Carcinoma Tumor cell Aromatic compound Tricyclic compound Cytotoxicity Mammary gland Glioblastoma Organic halogen compounds Human Nitrogen heterocycle In vitro Cell line Mitoxantrone Quinone Structure activity relation Chemical synthesis Central nervous system disease Nervous system diseases
- Keyword (es)
- Adición Diels Alder Anticanceroso Carcinoma Célula tumoral Compuesto aromático Compuesto tricíclico Citotoxicidad Glándula mamaria Glioblastoma Hombre Heterociclo nitrógeno In vitro Línea celular Mitoxantrona Quinona Relación estructura actividad Síntesis química Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16292714
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.09.021 
https://dx.doi.org/10.1016/j.bmc.2004.09.021
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