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Synthesis of tropeines and allosteric modulation of ionotropic glycine receptors

Author
MAKSAY, Gabor; NEMES, Péter; BIRO, Timea
Department of Chemistry, Faculty of Veterinary Sciences, Szent István University, Post Office Box 2, 1400, Budapest, Hungary
Molecular Pharmacology Group, Institute of Biomolecular Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Post Office Box 17, 1525, Budapest, Hungary
Source

Journal of medicinal chemistry (Print). 2004, Vol 47, Num 25, pp 6384-6391, 8 p ; ref : 28 ref

CODEN
JMCMAR
ISSN
0022-2623
Scientific domain
Pharmacology drugs
Publisher
American Chemical Society, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Acylate Animal Benzofurane dérivé Composé aromatique Hétérocycle azote In vitro Rat Relation structure activité Récepteur glycine Récepteur ionotropique Régulation allostérique Synthèse chimique Système nerveux central Sélectivité Tropane dérivé 8-Azabicyclo[3.2.1]octane dérivé Nortropan-3-ol benzoate[3-amino] Nortropane dérivé Tropan-3-ol benzoate Mammalia Rodentia Vertebrata
Keyword (en)
Acylate Animal Benzofuran derivatives Aromatic compound Nitrogen heterocycle In vitro Rat Structure activity relation Glycine receptor Ionotropic receptor Allosteric regulation Chemical synthesis Central nervous system Selectivity Tropane derivatives Mammalia Rodentia Vertebrata
Keyword (es)
Acilato Animal Compuesto aromático Heterociclo nitrógeno In vitro Rata Relación estructura actividad Receptor glicina Receptor ionotropico Regulación alostérica Síntesis química Sistema nervioso central Selectividad Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09E Glutamatergic system (aspartate and other excitatory aminoacids)

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16305175

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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