Syntheses of 2,4,6-trisubstituted pyrimidine derivatives as a new class of antifilarial topoisomerase II inhibitors
- Author
- SANJAY BABU KATIYAR1 ; BANSAL, Iti2 ; SAXENA, J. K2 ; CHAUHAN, P. M. S1
[1] Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226001, India
[2] Biochemistry Division, Central Drug Research Institute, Lucknow 226001, India - Source
Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 1, pp 47-50, 4 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antiparasitaire Antiprotozoaire DNA topoisomerase (ATP-hydrolysing) Hétérocycle azote In vitro Inhibiteur enzyme Pyrimidine dérivé Relation structure activité Synthèse chimique Theileria cervi Apicomplexa Enzyme Isomerases Protozoa
- Keyword (en)
- Parasiticide Antiprotozoal agent DNA topoisomerase (ATP-hydrolysing) Nitrogen heterocycle In vitro Enzyme inhibitor Pyrimidine derivatives Structure activity relation Chemical synthesis Theileria cervi Apicomplexa Enzyme Isomerases Protozoa
- Keyword (es)
- Antiparasitario Antiprotozoario DNA topoisomerase (ATP-hydrolysing) Heterociclo nitrógeno In vitro Inhibidor enzima Pirimidina derivado Relación estructura actividad Síntesis química Theileria cervi Apicomplexa Enzima Isomerases Protozoa
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16319961
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2004.10.046 
https://dx.doi.org/10.1016/j.bmcl.2004.10.046
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