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Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures

Author
QUNXING DING1 ; DIMAYUGA, Edgardo2 ; MARKESBERY, William R2 3 ; KELLER, Jeffrey N1 2
[1] Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky, United States
[2] Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States
[3] Department of Pathology and Neurology, University of Kentucky, Lexington, Kentucky, United States
Source

Journal of neurochemistry. 2004, Vol 91, Num 5, pp 1211-1218, 8 p ; ref : 1 p.1/4

CODEN
JONRA9
ISSN
0022-3042
Scientific domain
Cell biology, histology; Neurology; Physiology, morphology
Publisher
Blackwell, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
8-hydroxy-2'-deoxyguanosine Alzheimer's disease B-OHdG aging oxidative stress proteasome
Keyword (fr)
Accumulation biologique Astrocyte DNA Démence Alzheimer In vitro Mort cellulaire Multicatalytic endopeptidase complex Neurone Neurotoxicité Névroglie Oxydation RNA Stress oxydatif Sénescence Trouble neurologique Encéphale pathologie Enzyme Hydrolases Maladie dégénérative Peptidases Système nerveux central pathologie Système nerveux central Système nerveux pathologie
Keyword (en)
Biological accumulation Astrocyte DNA Alzheimer disease In vitro Cell death Multicatalytic endopeptidase complex Neuron Neurotoxicity Neuroglia Oxidation RNA Oxidative stress Senescence Neurological disorder Cerebral disorder Enzyme Hydrolases Degenerative disease Peptidases Central nervous system disease Central nervous system Nervous system diseases
Keyword (es)
Acumulación biológica Astrocito DNA Demencia Alzheimer In vitro Muerte celular Multicatalytic endopeptidase complex Neurona Neurotoxicidad Neuroglia Oxidación RNA Estrés oxidativo Senescencia Trastorno neurológico Encéfalo patología Enzima Hydrolases Enfermedad degenerativa Peptidases Sistema nervosio central patología Sistema nervioso central Sistema nervioso patología
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25C Isolated neuron and nerve. Neuroglia

Discipline
Vertebrates : nervous system and sense organs
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16331041

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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