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Novel cytotoxic thiodiketopiperazine derivatives from a Tilachlidium sp

Author
YUNJIANG FENG1 ; BLUNT, John W1 ; COLE, Anthony L. J1 ; MUNRO, Murray H. G1
[1] Department of Chemistry and School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
Source

Journal of natural products (Print). 2004, Vol 67, Num 12, pp 2090-2092, 3 p ; ref : 10 ref

CODEN
JNPRDF
ISSN
0163-3864
Scientific domain
Pharmacology drugs
Publisher
American Chemical Society, Washington, DC / American Society of Pharmacognosy, Glendale, AZ
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité biologique Analyse structurale Animal Anticancéreux Cellule tumorale Composé aromatique Composé bicyclique Composé pentacyclique Composé tétracyclique Cytotoxicité Disulfure organique Fungi Imperfecti Hétérocycle azote angulaire Hétérocycle azote Hétérocycle soufre azote In vitro Indole dérivé Isolement Lactame Leucémie P388 Lignée cellulaire Origine microbienne Souris Trisulfure organique 3,11a-Dithiopyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione(11-hydroxy-3-hydroxyméthyl-10b-indol-3-yl-2-méthyl-tétrahydro) 3,11a-Trithiopyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione(11-hydroxy-3-hydroxyméthyl-10b-indol-3-yl-2-méthyl-tétrahydro) Dithiopyrazinopyrroloindole Pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione(3,11a-bis[méthylthio]-11-hydroxy-3-hydroxyméthyl-10b-indol-3-yl-2-méthyl-tétrahydro) Pyrazinopyrroloindole Tilachlidium Trithiopyrazinopyrroloindole Fungi Mammalia Rodentia Thallophyta Vertebrata
Keyword (en)
Biological activity Structural analysis Animal Antineoplastic agent Tumor cell Aromatic compound Bicyclic compound Pentacyclic compound Tetracyclic compound Cytotoxicity Organic disulfide Fungi Imperfecti Angular nitrogen heterocycle Nitrogen heterocycle Sulfur nitrogen heterocycle In vitro Indole derivatives Isolation Lactam P388-Leukemia Cell line Microbial origin Mouse Organic trisulfide Fungi Mammalia Rodentia Thallophyta Vertebrata
Keyword (es)
Actividad biológica Análisis estructural Animal Anticanceroso Célula tumoral Compuesto aromático Compuesto bicíclico Compuesto pentacíclico Compuesto tetracíclico Citotoxicidad Disulfuro orgánico Fungi Imperfecti Heterociclo nitrógeno angular Heterociclo nitrógeno Heterociclo azufre nitrógeno In vitro Indol derivado Aislamiento Lactamo Leucemia P388 Línea celular Origen microbiano Ratón Trisulfuro orgánico Fungi Mammalia Rodentia Thallophyta Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05F Applied microbiology / 002A05F03 Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents / 002A05F03C Chemotherapic agents

Discipline
Microbiology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16417279

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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