Synthesis and in vivo biodistribution of BPA-Gd-DTPA complex as a potential MRI contrast carrier for neutron capture therapy
- Author
- TAKAHASHI, Kazunori1 ; NAKAMURA, Hiroyuki2 ; FURUMOTO, Shozo3 ; YAMAMOTO, Kazuyoshi4 ; FUKUDA, Hiroshi3 ; MATSUMURA, Akira5 ; YAMAMOTO, Yoshinori1
[1] Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan
[2] Department of Chemistry, Faculty of Science, Gakushuin University, Tokyo 171-8588, Japan
[3] Institute of Development, Aging and Cancer, Tohoku University, Sendai 980-8575, Japan
[4] Japan Atomic Energy Research Institute at Tokai, Ibaragi 319-1195, Japan
[5] Department of Neurosurgery, Institute of Clinical Medicine, University of Tsukuba, Ibaraki 305-8575, Japan - Source
Bioorganic & medicinal chemistry. 2005, Vol 13, Num 3, pp 735-743, 9 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acide pentétique Activité biologique Agent contraste paramagnétique Animal Bore Composé organique Boroneutronothérapie Boronique acide Captation Cellule tumorale Coordinat organique Distribution Gadolinium complexe Imagerie RMN In vivo Intestin Neutronthérapie Radiothérapie Rat Rayonnement gamma Rein Synthèse chimique Tissu Biodistribution Carbonate(éthyl 1-[4-(tributylsiloxy)butyl]allyl) Phénylalanine(4-dihydroxyboryl) ester éthyle Lanthanide complexe Mammalia Rodentia Vertebrata
- Keyword (en)
- Pentetic acid Biological activity Paramagnetic contrast agent Animal Boron Organic compounds Boron neutron capture therapy Boronic acids Uptake Tumor cell Organic ligand Distribution Gadolinium complex Nuclear magnetic resonance imaging In vivo Gut Neutron therapy Radiotherapy Rat Gamma radiation Kidney Chemical synthesis Tissue Rare earth metal complex Mammalia Rodentia Vertebrata
- Keyword (es)
- Acido pentético Actividad biológica Agente contraste paramagnético Animal Boro Compuesto orgánico Boroneutronoterapia Captación Célula tumoral Ligando orgánico Distribución Gadolinio complejo Imaginería RMN In vivo Intestino Neutronterapia Radioterapia Rata Radiación gama Riñón Síntesis química Tejido Lantánido complejo Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02T Contrast media. Radiopharmaceuticals
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04H Treatment. General aspects / 002B04H02 Treatment with physical agents / 002B04H02A Radiation therapy and radiosensitizing agent
- Discipline
- Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16427063
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.10.046 
https://dx.doi.org/10.1016/j.bmc.2004.10.046
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