Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant
- Author
- PORTIELJE, Johanna E. A1 ; KRUIT, Wim H. J1 ; EERENBERG, Anke J. M2 ; SCHULER, Martin3 ; SPARREBOOM, Alex1 ; LAMERS, Cor H. J4 ; GRATAMA, Jan-Willem4 ; STOTER, Gerrit1 ; HUBER, Christoph3 ; HACK, C. Erik2 5
[1] Department of Medical Oncology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, Netherlands
[2] Department of Immunopathology, CLB Sanquin Foundation, Amsterdam, Netherlands
[3] Department of Medicine III, Johannes Gutenberg University, Mainz, Germany
[4] Department of Medical and Tumor Immunology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Rotterdam, Netherlands
[5] VU Medical Center, Amsterdam, Netherlands - Source
Cancer immunology and immunotherapy. 2005, Vol 54, Num 1, pp 37-43, 7 p ; ref : 56 ref
- CODEN
- CIIMDN
- ISSN
- 0340-7004
- Scientific domain
- Biochemistry, molecular biology, biophysics; Medical oncology; Immunology, immunopathology, allergology
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Elastase Interleukin 12 Lactoferrin Neutrophils sPLA2
- Keyword (fr)
- Adjuvant Cytokine Homme Inflammation Injection Interleukine 12 Souscutané Vaccin Voie souscutanée
- Keyword (en)
- Adjuvant Cytokine Human Inflammation Injection Interleukin 12 Subcutaneous Vaccine Subcutaneous administration
- Keyword (es)
- Coadyuvante Citoquina Hombre Inflamación Inyección Interleuquina 12 Subcutáneo Vacuna Vía subcutánea
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16436179
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00262-004-0574-0 
https://dx.doi.org/10.1007/s00262-004-0574-0
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