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Prevention of irinotecan-induced diarrhea by oral sodium bicarbonate and influence on pharmacokinetics

Author
TAMURA, Takao1 ; YASUTAKE, Koichi1 ; KAMIGAKI, Takashi3 ; KASUGA, Masato2 ; NISHISAKI, Hogara1 ; NAKASHIMA, Takatoshi1 ; HORITA, Kazutugu1 ; HIROHATA, Sigeya1 ; ISHII, Arata1 ; HAMANO, Kenichi1 ; AOYAMA, Nobuo2 ; SHIRASAKA, Daisuke2
[1] Department of Gastroenterology, Hyogo Medical Center for Adults, Hyogo, Japan
[2] Division of Diabetes, Digestive and Kidney Diseases, Kobe University Graduate School of Medicine, Kobe, Japan
[3] Division of Gastroenterological Surgery, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
Source

Oncology. 2004, Vol 67, Num 5-6, pp 327-337, 11 p ; ref : 38 ref

ISSN
0030-2414
Scientific domain
Medical oncology
Publisher
Karger, Basel
Publication country
Switzerland
Document type
Article
Language
English
Author keyword
Delayed diarrhea Irinotecan hydrochloride Oral alkalization SN-38 Sodium bicarbonate
Keyword (fr)
Anticancéreux Cancérologie Diarrhée Hydrogénocarbonate Irinotécan Pharmacocinétique Prévention Sodium Voie orale Camptothécine dérivé Pyrano indolizino quinoléine dérivé Appareil digestif pathologie DNA topoisomerase Enzyme Inhibiteur enzyme Intestin pathologie Isomerases
Keyword (en)
Antineoplastic agent Cancerology Diarrhea Hydrogencarbonates Irinotecan Pharmacokinetics Prevention Sodium Oral administration Digestive diseases DNA topoisomerase Enzyme Enzyme inhibitor Intestinal disease Isomerases
Keyword (es)
Anticanceroso Cancerología Diarrea Hidrógenocarbonato Irinotecán Farmacocinética Prevención Sodio Vía oral Aparato digestivo patología DNA topoisomerase Enzima Inhibidor enzima Intestino patología Isomerases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16449093

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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