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Structural rearrangements in RNA on the binding of an antisense oligonucleotide: implications for the study of intra-molecular RNA interactions and the design of cooperatively acting antisense reagents with enhanced efficacy

Author
SOHAIL, Muhammad1 ; DORAN, Graeme1 ; KANG, Swan1 ; AKHTAR, Saghir2 ; SOUTHERN, Edwin M1
[1] Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3Q, United Kingdom
[2] Centre for Genome-Based Therapeutics, Welsh School of Pharmacy, Cardiff University, Cardiff, Wales, United Kingdom
Source

Journal of drug targeting. 2005, Vol 13, Num 1, pp 61-70, 10 p ; ref : 41 ref

ISSN
1061-186X
Scientific domain
Pharmacology drugs
Publisher
Taylor & Francis, Abington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Cooperative RNA structure RNase H assay antisense oligonucleotide array oligonucleotide library
Keyword (fr)
Calf thymus ribonuclease H Conception Dosage Interaction moléculaire Liaison Oligonucléotide antisens RNA Réactif Technologie pharmaceutique Enzyme Esterases Hydrolases
Keyword (en)
Calf thymus ribonuclease H Design Assay Molecular interaction Binding Antisense oligonucleotide RNA Reagents Pharmaceutical technology Enzyme Esterases Hydrolases
Keyword (es)
Calf thymus ribonuclease H Diseño Dosificación Interacción molecular Enlace Oligonucleótido antisentido RNA Reactivo Tecnología farmacéutica Enzima Esterases Hydrolases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
16517810

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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