Novel thiocoumarins as inhibitors of TNF-α induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) and microsomal lipid peroxidation
- Author
- KUMAR, Sarvesh1 ; SINGH, Brajendra K2 ; KALRA, Neerja2 ; KUMAR, Vineet2 ; KUMAR, Ajit3 ; PRASAD, Ashok K2 ; RAJ, Hanumantharao G3 ; PARMAR, Virinder S2 ; GHOSH, Balaram1
[1] Molecular Immunogenetics Laboratory, Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India
[2] Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi-110 007, India
[3] Department of Biochemistry, V.P. Chest Institute, University of Delhi, Delhi-110007, India - Source
Bioorganic & medicinal chemistry. 2005, Vol 13, Num 5, pp 1605-1613, 9 p ; ref : 37 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antiinflammatoire Antioxydant Cellule endothéliale Cordon ombilical Coumarine dérivé Facteur nécrose tumorale α In vitro Inhibiteur Lignée cellulaire Lipide Peroxydation Phénols Protéine CAM Protéine ICAM1 Relation structure activité Relation structure fonction Synthèse chimique Thiolactone Veine ombilicale 1-Benzopyrane-2-thione(7-hydroxy-4-méthyl) Lignée HUVEC
- Keyword (en)
- Antiinflammatory agent Antioxidant Endothelial cell Umbilical cord Coumarine derivatives Tumor necrosis factor α In vitro Inhibitor Cell line Lipids Peroxidation Phenols Cell adhesion molecule Intercellular adhesion molecule 1 Structure activity relation Structure function relationship Chemical synthesis Thiolactone Umbilical vein
- Keyword (es)
- Antiinflamatorio Antioxidante Célula endotelial Cordón umbilical Factor necrosis tumoral α In vitro Inhibidor Línea celular Lípido Peroxidación Fenoles Proteína CAM Proteína ICAM1 Relación estructura actividad Relación estructura función Síntesis química Tiolactona Vena umbilical
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16518163
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2004.12.013 
https://dx.doi.org/10.1016/j.bmc.2004.12.013
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