New aminocoumarin antibiotics from genetically engineered Streptomyces strains
- Author
- LI, S.-M1 ; HEIDE, L1
[1] Pharmazeutische Biologie, Pharmazeutisches Institut, Eberhard-Karls-Universität Tübingen, Anf der Morgenstelle 8, 72076 Tübingen, Germany - Source
Current medicinal chemistry. 2005, Vol 12, Num 4, pp 419-427, 9 p ; ref : 34 ref
- ISSN
- 0929-8673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Bentham Science, Schiphol
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Aminocoumarin Streptomyce chemoenzymatic synthesis combinatorial biosynthesis heterologous expression mutasynthesis
- Keyword (fr)
- Antibactérien Antibiotique Chlorobiocine Coumarine dérivé DNA topoisomerase (ATP-hydrolysing) Glycoside Génie génétique In vitro Inhibiteur enzyme Lactone Mutation Novobiocine Relation structure activité Réaction enzymatique Streptomyces coelicolor Synthèse chimique BIosynthèse combinatoire Coumémycine Novclobiocine Actinomycetales Actinomycetes Bactérie Enzyme Isomerases Streptomycetaceae
- Keyword (en)
- Antibacterial agent Antibiotic Coumarine derivatives DNA topoisomerase (ATP-hydrolysing) Glycoside Genetic engineering In vitro Enzyme inhibitor Lactone Mutation Novobiocin Structure activity relation Enzymatic reaction Streptomyces coelicolor Chemical synthesis Combinatorial biosynthesis Actinomycetales Actinomycetes Bacteria Enzyme Isomerases Streptomycetaceae
- Keyword (es)
- Antibacteriano Antibiótico DNA topoisomerase (ATP-hydrolysing) Glicósido Ingeniería genética In vitro Inhibidor enzima Lactona Mutación Novobiocina Relación estructura actividad Reacción enzimática Streptomyces coelicolor Síntesis química Actinomycetales Actinomycetes Bacteria Enzima Isomerases Streptomycetaceae
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05F Applied microbiology / 002A05F03 Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents / 002A05F03B Antibiotics (antibacterial agents, antifungal agents)
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31C Methods. Procedures. Technologies / 002A31C06 Bioconversions. Hemisynthesis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S01 General aspects
- Discipline
- Biotechnology Microbiology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16525159
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/0929867053363063 
https://dx.doi.org/10.2174/0929867053363063
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